The Naked Scientists Podcast - Stripping Down Science

Microbiome links to Parkinson's, and a massive laser boost

This week scientists confirm the link between changes to the microbiome and later development of Parkinson's Disease, a super speedy microfluidic way to diagnose infection and probe antibiotic susceptibility, how many infections does daycare cause in your toddler, and the breakthrough capable of boosting laser power by orders of magnitude…

24 Apr 32 min

What is flooding? And how do we tackle it?

We dive into the science and impact of flooding and coastal change. In partnership with UK Research and Innovation, this podcast explores what flooding is, how we measure tides, the dangers flooding presents to people and places, and how computing and AI are helping us predict, manage, and reduce its…

20 Apr 28 min

Alzheimer's drugs & tackling HIV

This week, we look at UK Alzheimer's drugs and the latest debate over whether new treatments are a genuine breakthrough or overhyped, alongside a striking HIV case from Oslo that has raised fresh questions in medical research. We also explore new findings on gut health and its link to hormones…

16 Apr 30 min

Oil, gas & what comes next

This week, we are exploring the oil and gas industry, literally from the ground up: what's the geology of oil formation, how does a petrochemist go from crude to highly refined, can the UK solve its energy price problem by actually using the oil on its own doorstep, and what…

14 Apr 33 min

Space travel alters the body, and chronic pain on the mind

This week, we find out how space travel is likely to affect the bodies of the Artemis II astronauts. Plus, how conflict and other adverse events during childhood influence young lives, what is the link between chronic pain, stress and the brain, and how male octopuses use a specialised arm…

9 Apr 34 min

What is time?

Time waits for no one, but what exactly is it? Is it just a human construct, or something far deeper, flowing through our minds and bodies? In this episode, we examine the very fabric of time: how we created it, how we perceive it, the hidden rhythms of our body…

7 Apr 33 min

Artemis II launch, and tackling physical inactivity

Artemis II begins its mission to take humans farther into space than ever before, scientists in London unveil the first lab-grown oesophagus, the dangers of physical inactivity and why we urgently need to tackle it, and brain cells on a chip learn to play video games like humans... Like this…

3 Apr 34 min

Nature frozen in time

Across our planet, natural archives preserve the biological footprints of species long gone, from woolly mammoths at the macro scale, through plants and seeds, to dormant bacteria and viruses at the micro end of the spectrum. And one environment that safeguards some of this material in the best condition of…

31 Mar 29 min

Social media addiction, and the famous honeybee dance

This week: social media's role in user harm and the plausibility of app addiction, a sunken Soviet sub revealing how nuclear materials behave deep underwater, a hidden "magnetic shadow" on the Moon that could improve space travel safety, and the science behind the famous "waggle dance" performed by honeybees.... Like…

27 Mar 31 min

Return to the Moon

Coming up, we explore the race back to the Moon. Why are we going? How will we get there? Can we live and work on its surface? And what can we grow when we get there? We explore the science, the engineering, and the possibilities of humanity's next giant leap…

24 Mar 32 min

Meningitis in Kent, and sonic hedgehogs

Coming up, we explore an outbreak of meningitis in the English county of Kent. Will a targeted vaccination campaign bring it under control? Plus, a fast diagnostic swab test that may help diagnose schizophrenia, how thousands of old tumour samples could aid our understanding of rising bowel cancer rates in…

19 Mar 31 min

Understanding endometriosis

For Endometriosis Awareness Month, we explore a condition which affects 10% of women around the world. Cells that form the lining of the uterus crop up in other parts of the pelvis, and elsewhere in the body. It prevents many patients from being able to carry out everyday tasks, and…

17 Mar 31 min

War and the environment, and Neanderthal-human interbreeding

Coming up, we assess the environmental and health impact of conflict in the Middle East. Plus, the gene variants that affect how heavily someone smokes, a medication called ruxolitinib that could help the vitiligo community, and a fascinating new study on interbreeding between Neanderthals and humans... Like this podcast? Please…

12 Mar 31 min

Eradicating polio

This week, we're exploring polio: a highly infectious viral disease that can attack the nervous system and cause paralysis, mainly in young children. Polio has been pushed to the brink of elimination thanks to global vaccination efforts - but it still persists. In this episode, we'll look at what polio…

9 Mar 31 min

Immune reprogramming for cancer, and squeaky shoe science

Coming up, we explore how CAR-T cell therapy is revolutionising personalised cancer treatment. Plus, how NASA's DART mission tested Earth's asteroid defence, what we are learning about the benefits of breastfeeding for mother and baby health, and we delve into the physics behind squeaky shoes... Like this podcast? Please help…

6 Mar 31 min

Titans of Science: Mike Wooldridge

Our Titans of Science series continues with Mike Wooldridge, Ashall Professor of Foundations of Artificial Intelligence at the University of Oxford. He has conducted extensive work in the field of agentic AI, systems comprising multiple interacting AIs. In this episode, he tells Chris Smith what drew him to computers and…

3 Mar 32 min

Brain fats cleared during sleep, and bird poo powered Peru

Today, how the brain harnesses immune cells to clear burned out fats during sleep: does this protect from Alzheimer's disease? Also, the nutrient-rich guano of seabirds that shaped society in ancient Peru, fast footage reveals how kangaroos hop faster at no extra energy cost, and how horses whinny! Like this…

27 Feb 33 min

Titans of Science: Jane Carlton

Our Titan of Science this week is leading light in the field of malaria, Jane Carlton. The first to sequence the genome of malaria parasite Plasmodium vivax, she also helped sequence the deadlier Plasmodium falciparum. Jane tells Chris Smith the ins and outs of malaria, her journey to become Director…

24 Feb 30 min

Navalny's dart frog poisoning, and cat cancer genomics

This week, we look into the science behind Russian opposition leader Alexei Navalny's death, caused by dart frog poison, and why Russia resorted to such an exotic means of dispatch at all. Also, how cat cancer genomics can provide new insights into human malignancies, and - more with a whimper…

20 Feb 29 min

Heart failure: can you mend a broken heart?

This week, in partnership with British Heart Foundation, we explore heart failure. Leading experts from the UK's largest independent funder of cardiovascular research tell us about the condition, the symptoms to look out for, what happens when a heart fails, how heart failure has traditionally been managed, and whether it…

17 Feb 28 min